A recent article from the National Hog Farmer has illustrated the outstanding research developing PRRS-resistant pigs carried out by researchers at the University of Missouri, Kansa State University and Genus plc.
Porcine Reproductive and Respiratory Syndrome virus is a virus that causes diseases in pigs. It can cause reproductive failure as well as respiratory tract illness in infected pigs, leading to serious health problems which can have a devasting economic impact on breeding stock.
The University of Missouri were able to isolate the CD163 protein thought to help PRRS spread in internally in pigs by uncoating the virus. Further research using gene-editing systems including CRISPR/Cas9 were able to stop pigs producing the CD163 protein and thereofre the virus is unable to uncoat, pigs do not recognise the virus and they therefore do not get ill.
Further challenge experiments were carried out to provide further support to the genetic experimental research.
To read the full article please visit the National Hog Farmer Website