The Roslin Institute
Cattle vaccine development targeting Enterohaemorrhagic E. coli; I have been involved in this area for 10 years with a number of industry partners; Use of flagellin as a mucosal adjuvant; Identification of bacterial surface and secreted antigens to be included in vaccines.
1. Development of EHEC vaccines for use in cattle.
2. Research into flagellin adjuvancy
3. Research aimed at understanding how bacteriophage manipulate animal innate and adaptive immunity and consideration for the use of more phage-based vaccines.