1. Studying the pathogenesis of malignant catarrhal fever (MCF) in cattle as well as in the rabbit and hamster models of disease.
2. Development and improvement of a vaccine to MCF. The importance of the route of immunisation, and testing various adjuvants based on TLR ligands amongst others.
3. Studying polymorphic variants of toll-like receptors in cattle and sheep. Differences between ruminant TLRs and those of the human and mouse.