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David Haig
0115 951 6450
University of Nottingham
Innate immunity, adaptive immune mechanisms in disease, toll-like receptor polymorphic variants and biology, vaccine design, pathogenesis and control of herpesviruses
1. Studying the pathogenesis of malignant catarrhal fever (MCF) in cattle as well as in the rabbit and hamster models of disease.
2. Development and improvement of a vaccine to MCF. The importance of the route of immunisation, and testing various adjuvants based on TLR ligands amongst others.
3. Studying polymorphic variants of toll-like receptors in cattle and sheep. Differences between ruminant TLRs and those of the human and mouse.