I graduated from the University of Bristol with degrees in Cellular Pathology and Veterinary Science, studied for a postgraduate diploma in Veterinary Pathology at Cornell University in the United States and obtained my PhD in immunology and parasitology from the University of Liverpool. I then worked full time for 5 years, and part-time for another 5 years, at the Medical Research Council Laboratories in The Gambia. From 1990 to 1998 I was a Wellcome Trust Senior Research Fellow at The University of Edinburgh. I was appointed Professor of Infectious Disease Immunology at the London School of Hygiene and Tropical Medicine in October 1998 and was Head of the Department of Immunology and Infection in the Faculty of infectious and Tropical Diseases from 2001 to 2013. I was eelcted a Fellow of the Academy of Medical Sciences in 2014. I am curently Chair of the BBSRC Bioscience for Health strategy advisory panel.