My research is focused on the study of the immune responses in situ at the site of infection in animal models of disease and vaccination trials, including: a) the differences on the pathological and cytokine/chemokine phenotypic presentation of bovine tuberculosis in cattle after BCG vaccination and challenge with pathogenic Mycobacterium bovis strains; b) the study of immune responses after vaccination and/or infection with classical swine fever virus, PRRS virus and Mycoplasma spp. in swine, by using modern technologies to identify possible biomarkers of protection and disease severity