The main focus of my research involves using a combination of molecular biology and proteomics to investigate interactions between parasites and their hosts, and applying this information towards the development of anti-parasite vaccines. I am currently involved in a project to develop a vaccine against the salmon louse, Lepeophtheirus salmonis, which is an economically important parasite of both wild and farmed salmon in the UK and further afield. I am also interested in vaccine development for other veterinary and aquatic parasite species.
One of my main research interests is the study of excreted/secreted parasite products which may potentially affect the host's immune response (immunomodulation). Many parasites secrete products which alter the immune response of the host for the parasite's benefit. I believe that these immunomodulatory products can be exploited for use in novel vaccines. I am also interested in recombinant protein production for use in anti-parasite vaccines.